1. WHAT LOCOID LIPOCREAM IS AND WHAT IT IS USED FOR

Locoid Lipocream contains an adrenal cortex
hormone (corticosteroid) and decreases quickly
the symptoms such as itching, redness or scaling
of the skin, which occur in certain skin disorders.
Corticosteroids in general do not cure the
underlying disease.
The cream base provides for the skin disorder to
become less moist.
Locoid Lipocream may be used for the treatment
of superficial skin diseases in which itching,
redness or scaling are often present.
Locoid Lipocream contains more fat than normal
and is therefore suitable for those skin disorders
where the skin can be partly dry yet still partly
moist.

2. BEFORE YOU USE LOCOID LIPOCREAM
Do NOT use Locoid Lipocream
• If you are allergic (hypersensitive) to
hydrocortisone-17-butyrate or any of the other
ingredients of Locoid Lipocream.
• If you have a skin disorder caused by bacterial,
viral, fungal, yeast or parasitic infections. These
disorders might aggravate or be masked.
• If you have acne, also with redness of the skin.
• If you have wounds or fish skin (ichtyosis).
• If you have a skin disorder which might result
from previous treatment with corticosteroids,
such as inflammation of the skin around the
mouth, thin skin, possibly with stripes, fragile
blood vessels.
• With rash on the footsoles of children.
 

Take special care with Locoid Lipocream
• The skin of the face, the skin of the genitals
and skin folds are particularly sensitive
to corticosteroids and should be treated
cautiously.
• Examination by your doctor is necessary if
you use Locoid Lipocream under bandages or
dressings, on large skin areas or in children.
• Locoid Lipocream should not be used in the
eye or on the eyelids.
• Long-term use of corticosteroids on large
parts in children should be avoided.
Consult your doctor if one of the abovementioned
warnings is applicable to you.
If after long-term treatment with Locoid
Lipocream the skin disorder quickly returns, you
should consult your doctor.
 

Using other medicines, herbal or dietary
supplements Please note: The following
remarks may also be applicable to the use of
medicines in the recent past or near future.
Please inform your doctor or pharmacist if you
are taking or have recently taken any other
medicines. This also applies to medicines
available without prescription.
 

Pregnancy
The use of high doses of corticosteroids can
cause growth retardation of the unborn child.
Because only a small amount of active
substance is released in the blood when using
Locoid Lipocream, Locoid Lipocream can be used
for a short period and on small parts of the skin.
The above-described effect cannot be ruled out
on long- term treatment or application on larger
skin areas.
Ask your doctor or pharmacist for advice before
using any medicine. If you want to use Locoid
Lipocream during pregnancy, please consult your
doctor first.
 

Breastfeeding
Locoid Lipocream can be used by nursing
mothers if the treatment is short-term and the
product is applied to small areas. Breastfeeding
is not advised on long-term treatment or when
large areas are being treated.
Ask your doctor or pharmacist for advice before
using any medicine. If you want to use Locoid
Lipocream during breastfeeding, please consult
your doctor first.

Driving and using machines
There are no data on the effects of Locoid
Lipocream on the ability to drive or to operate
machinery, but Locoid Lipocream is not expected
to exert any influence.

Important information about some of the
ingredients of Locoid Lipocream
Cetostearyl alcohol can cause local skin
reactions (e.g. contact dermatitis).
Propyl parahydroxybenzoate can cause allergic
reactions (possibly delayed).

3. HOW TO USE LOCOID LIPOCREAM
Always use Locoid Lipocream exactly as your
doctor or pharmacist has told you.
Locoid Lipocream should be applied in a thin
layer on the diseased skin. After application you
may carefully massage Locoid Lipocream into
the skin. Do not apply more than 1 to 3 times
daily on the diseased skin, unless your doctor
prescribes otherwise.
If your complaints decrease your doctor may
advise you to use Locoid Lipocream less often.
In general you should not use more than 1–2
tubes of 30 gram Locoid Lipocream per week.
Sometimes your
doctor may advise you to alternate Locoid
Lipocream with Locoid ointment or Locoid cream
and vice versa.
 

If you use more Locoid lipocream than you
should
If you have used too much Locoid Lipocream,
side effects as described below under “4.
Possible side effects” may occur. If this is
the case, immediately contact your doctor or
pharmacist.
 

If you forget to use Locoid lipocream
If you forget once to apply Locoid Lipocream, you
may continue with Locoid Lipocream as usual.
It is not necessary to apply an extra amount of
Locoid Lipocream.

If you stop using Locoid lipocream
If treatment with Locoid Lipocream is stopped
too early, the initial symptoms may return.
Always consult your doctor, if you consider
stopping treatment.
If you have any further questions on the use of
this product, ask your doctor or pharmacist.

4. POSSIBLE SIDE EFFECTS
Like all medicines, Locoid Lipocream can cause
side effects, although not everybody gets them.
The following side effects may occur when using
Locoid Lipocream:
Immune system disorders
 

Very rare (in less than 1 in 10,000 patients)
• Hypersensitivity
Hormonal disorders

Rare (in more than 1 in 10,000, but less than
1 in 1,000 patients)
• Adrenocortical suppression
In case of long-term treatment with
corticosteroids applied to the skin, they can
penetrate the skin and enter the blood. This may
lead to adrenocortical suppression. The risk of
systemic side effects is highest in the case of:
- Application under occlusion (under plastic, in
skin folds)
- Application to large areas of skin
- Long-term treatment
- Use in children
Eye disorders

Very rare (in less than 1 in 10,000 patients)
• Increased intraocular pressure with increased
risk of cataract.
Skin and subcutaneous tissue disorders

Rare (in more than 1 in 10,000, but less than
1 in 1,000 patients)
• Burning sensation or itching of the skin treated
with Locoid Lipocream. This is mostly not
serious and disappears of its own.
• Discolouration or thinning of the skin (often
irreversible), sometimes with stripes (striae),
widening of the bloodvessels in the skin,
excessive hairgrowth (hypertrichosis).
• Worsening of the skin disease after stopping of
treatment (“rebound-effect”).
• Rash, pimples or purulence, if you use Locoid
Lipocream for a long time or under occlusion.
• Eczema or inflammation of the skin
(dermatitis), including skin inflammation as a
result of contact with irritating substances or
substances causing hypersensitivity (contact
dermatitis).

5. STORING LOCOID LIPOCREAM
Keep Locoid Lipocream out of reach and sight of
children.
Do not store Locoid Lipocream above 25°C.
Do not store in the refrigerator or freezer.
Do not use Locoid Lipocream after the expiry
date which is stated on the tube and carton after
{EXP}. The expiry date refers to the last day of
that month