Metaz Cream 0.1%

Each gram contains 1mg Mometasone Furoate.

Metaz Ointment 0.1%

Each gram contains 1mg Mometasone Furoate.

ACTIONS:

Mometasone furoate, a synthetic corticosteroid, exhibits anti-inflammatory, antipruritic, and vasoconstrictive properties.

INDICATIONS AND USAGE:

Metaz Cream and Ointment 0.1% are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, such as psoriasis and atopic dermatitis.

CONTRA-INDICATIONS:

Metaz Cream and Ointment 0.1% are contraindicated in patients who are sensitive to mometasone furoate, to other corticosteroids, or to any component of these preparations.

Metaz Cream and Ointment 0.1% are also contraindicated in fungal, tubercular skin infections or viral skin infections such as herpes simplex or zoster, facial rosacea, acne vulgaris & perioral dermatitis.

PRECAUTIONS:

If irritation or sensitization develops with the use of Metaz products, treatment should be discontinued and appropriate therapy instituted.

In the presence of an infection, the use of an appropriate antifungal or antibacterial agent should be instituted. If a favorable response does not occur promptly, the corticosteroid should be discontinued until the infection is controlled adequately.

Any of the side effects that have been reported following systemic use of corticosteroids, including adrenal suppression, may also occur with topical corticosteroids, especially in infants and children.

Systemic absorption of topical corticosteroids will be increased if extensive body surface areas are treated or if the occlusive technique is used. Suitable precautions should be taken under these conditions or when long-term use is anticipated, particularly in infants and children. Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced hypothalamic-pituitary axis suppression and Cushing’s syndrome than mature patients because of a larger skin surface area to body weight ratio. The use of topical corticosteroids in children should be limited to the least amount compatible with an effective therapeutic regimen. Chronic corticosteroid therapy may interfere with the growth and development of children.

Since the safe use of Metaz products in pregnant women has not been established, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used on pregnant patients in large amounts or for prolonged periods of time. It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in breast milk. Systemically administered corticosteroids are secreted into breast milk in quantities not likely to have a deleterious effect on the infant. Nevertheless, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Excessive, prolonged use of topical corticosteroids can suppress pituitary-adrenal function resulting in secondary adrenal insufficiency. Appropriate symptomatic treatment is indicated. Acute hypercorticoid symptoms are virtually reversible. Treat electrolyte imbalance, if necessary. In cases of chronic toxicity, slow withdrawal of corticosteroids is advised.

Metaz products are FOR DERMATOLOGICAL USE ONLY, these are NOT FOR OPHTHALMIC USE.

DOSAGE AND ADMINISTRATION:

A thin film of Metaz Cream or Ointment 0.1% should be applied to the affected skin areas once daily.

Local adverse reactions rarely reported with mometasone furoate include burning, pruritus, paresthesia, tingling/stinging, acneiform reaction, folliculitis, and signs of skin atrophy.

The following local adverse reactions have been reported infrequently with the use of other topical corticosteroids; irritation, hypertrichosis, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, striae, and miliaria.

Store below 30° C.

Keep out of the reach of children.

For external use only.