1. What Mentex is and what it is used for

Mentex is a non-narcotic, antitussive, decongestant and expectorant to give comprehensive  relief  to  the  coughing  patient.

Diphenhydramine Hydrochloride is a H1-antagonist. It is used for symptomatic relief of hypersensitivity reactions by blocking the histamine receptors on tissues.

Dextromethorphan  Hydrobromide  suppresses  the cough reflex by direct  action on the cough center  in the medulla.

Pseudoephedrine  Hydrochloride is  indirectly acting  sympathomimetic  agent.  It  is  used  primarily  for  decongestion  of  nasal mucosa and eustachian  tubes. Combination  with  antihistamine   may  provide additive benefit in seasonal allergic rhinitis, because antihistamines alone do not relieve nasal stuffiness.

Ammonium Chloride and Sodium Citrate are acting expectorants and they are useful especially when it is desired to liquefy thick tenacious sputum.

Menthol has an antitussive action due to its local analgesic effect.

Mentex is used for the relief of cough and its congestive symptoms and in the treatment of hay fever and other allergic conditions affecting the upper respiratory tract.  You should contact your doctor if symptoms persist.

2. Before you take Mentex

Do not take Mentex

- If you have previously exhibited intolerance to it or to any of its ingredients.

- If you have severe hypertension or coronary artery disease.

- This medication should not be used for the treatment of cough and cold symptoms in children under 12 years of age.

Take special care with Mentex

Tell your doctor before taking this medicine:

- If you have severe hepatic dysfunction.

- If you have severe renal dysfunction.

In the above cases, dosage adjustment is recommended.

- If you have hypertension.

- If you have narrow-angle glaucoma.

- If you have prostatic hypertrophy.

- If you have bladder-neck obstruction.

- If you have ischemic heart disease.

- If you have hyperthyroidism.

- If you are a diabetic patient.

If symptoms did not improve during 7 days or if they were accompanied by fever, you should see the doctor.

- Prolonged use of product containing dextromethorphan such as Mentex may lead to drug dependence (addiction), even at therapeutic doses. The risks are increased if you have current or past history of substance misuse disorder (including alcohol misuse) or mental health disorder (e.g., major depression). Caution is particularly recommended if you are an adolescents or a young adult as well as if you have history of drug abuse or psychoactive substances.

- As with other CNS stimulants, pseudoephedrine sulphate carries the risk of abuse. Increased doses may ultimately produce toxicity. Continuous use can lead to tolerance resulting in an increased risk of overdosing.

Taking other medicines

Please inform your doctor or pharmacist if you are taking, or have recently taken, any other medicines, including those medicines obtained without a prescription.

Especially, tell your doctor if you are taking the following medicines:

- Other sympathomimetics decongestants.

- Appetite suppressants.

- Amphetamine and amphetamine like psycostimulants.

- Antihypertensive agents.

- Antihistamines.

Concomitant use of  Mentex and Monoamine Oxidase (MAO) inhibitors could cause a rise in blood pressure.

Pregnancy and Lactation

Care should be taken in administration during pregnancy.

Driving and using machines

Caution should be taken in driving or operating machinery, as Mentex may cause drowsiness.

Important information about some ingredients of Mentex

If you have been told by your doctor that you have an intolerance to some sugars or if you are a diabetic patient, you should take care as Mentex contains 3.25 g sucrose per 5 mL of syrup.

3. How to take Mentex

Adults: 5 mL every four to six hours.

If you take more Mentex than you should

In  case  of  overdosage, the  following measures should be taken:

- Gastric lavage.

- Treatment with diazepam to control convulsions.

- Supportive symptomatic treatment.

4. Possible side effects

Diphenhydramine may cause: drowsiness, dizziness, gastrointestinal disturbance, dry mouth, nose and throat, difficulty in urination or blurred vision.

Dextromethorphan may cause: dizziness, nausea, vomiting, gastro-intestinal disturbance and psychiatric disorders (drug dependence with an unknown frequency).

Adverse reactions to menthol at the low concentration present in Mentex are not anticipated.

Pseudoephedrine may cause: Nervousness, restlessness and trouble in sleeping.

In general:

Epigastric discomfort, loss of appetite, nausea, vomiting, diarrhea or constipation, tachycardia, palpitation, ECG changes, arrhythmias, hypotension,hypertension, bronchial secretions darkening, hypersensitivity reactions, sensitivity to light, and can be seen in cross-sensitivity to chemically similar preparations. especially in patients with prostatic hypertrophy, urinary retention is reported to be. Rare side effects: dizziness, tremor, and rarely hallucinations, sleep disturbances, headaches, coordination difficulties, skin rashes, fotosensitive, dryness of the throat.

If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

5. How to store Mentex

Keep out of reach of children.

Store below 30°C.

After opening, it should be used within one month.

Do not use beyond the expiry date or if the product shows any sign of deterioration.

Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help to protect the environment.