is used to treat long-term recurring  constipation in women in whom laxatives do not work well enough.

WHEN NOT TO TAKE Resolor™

Do not take if you:

•  are allergic (hypersensitive) to prucalopride or any of the other ingredients of Resolor™,

•  have severe kidney disease and are  on kidney (renal) dialysis,

•  have a torn (perforated) or blocked gut (intestines) or other gut problemssuch as Crohn’s disease, ulcerative colitis or toxic megacolon/megarectum.

 WHAT SPECIAL PRECAUTIONS SHOULD YOU TAKE?

Take special care with Resolor™ if you:

•  have severe kidney problems,

•  have severe liver problems,

•  have a serious medical problem such as: lung or heart problems, cancer or AIDS.

If you have very bad diarrhoea and are taking a contraceptive pill, the contraceptive pill may not work properly and you should talk to your doctor about other contraception methods.

 Children

Resolor™ should not be given to children under 18 years.

 Pregnancy

If you are of c hild be aring age, you s hould t alk t o your doc tor ab out c ontraception dur ing treatment w ith Resolor™. Resolor™ is not r ecommended dur ing pr egnancy.  If y ou ar e, pregnant, or you think you may be pregnant, or if you are planning to become pregnant, talk to your doctor about the risks and benefits of taking Resolor™. 

 Breast-feeding

You are advised not to take Resolor™ if you are breast- feeding, because small amounts of Resolor™ can be passed on to your baby in breast milk. If you are breast-feeding or thinking about breast-feeding talk to your doctor. .

 Driving or operating machinery

Resolor™ may cause dizziness and tiredness, especially on t he first day of treatment which may make you less alert. Don’t drive or use machines unless you are sure you are not affected.  

 Other medicines

Please t ell your doc tor or phar macist i f you ar e t aking or ha ve r ecently t aken an y other medicines. This includes medicines that you buy without a prescription or herbal medicines. 

Resolor™ comes in the form of film coated tablets to be taken by mouth.  You can take Resolor™ with or without food and drinks, at any time of the day.

Always take Resolor™ exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. You should take Resolor™ every day for as long as your doctor prescribes it.

Your doctor may check how well Resolor™ is working after the first 4 w eeks and r egularly after that.

Adults (including people over 65 years)  

The usual dose of Resolor™ for adults is one 2 m g tablet once a day . If you are older than 65 years, the usual starting dose is one 1 mg tablet once a day, which your doctor may increase to 2 mg once a day if needed.

Your doctor may also prescribe a lower dose of one 1 mg tablet daily if you have  kidney or liver problems.

Resolor™ is only for adult women and s hould not be taken by children and adol escents up t o 18 years.

If you take more Resolor™ than you should

It is important to keep to the dose as prescribed by your doctor. If you have taken more Resolor™ than you should, you may get diarrhoea, headache and/or nausea. If you get diarrhoea, make sure that you drink more water than usual and ask your doctor or pharmacist for further advice.

If you forget to take Resolor™

If you forget to take a do se, take it as soon as you remember and t hen continue treatment as before. Do not take a double dose to make up for a missed dose. 

If you stop taking Resolor™

If you stop taking Resolor™, your constipation may come back again. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Important information about some of the ingredients of Resolor™

Resolor™ contains lactose monohydrate. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.

Like all medicines, Resolor™ can cause side effects, although not everybody gets them. The side effects usually happen  when you first start using Resolor™ and usually disappear within a few days..

Very common side effects

These may affect more than 1 in 10 people

•  Headache

•  Feeling sick (nausea)

•  Diarrhoea 

•  Stomach pain

Common side effects

These may affect up to 1 in 10 people

•  Dizziness

•  Vomiting

•  Disturbed digestion (dyspepsia)

•  Rectal bleeding

•  Windiness (flatulence)

•  Unusual bowel sounds

•  Need to pass urine more often than usual (pollakiuria)

•  Tiredness

Uncommon side effects

These may affect up to 1 in 100 people

•  Loss of appetite (anorexia)

•  Shaking (tremors)

•  Fever

•  Weakness

•  Pounding heart (palpitations) If you get a pounding heart, tell your doctor straight away as you may need medical attention.

If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

Keep out of the reach and sight of children.

This medicine c an be k ept f or onl y a l imited per iod. D o not us e Resolor™ after t he dat e (month and year) printed after “EXP”, even if it has been stored properly.

Store in the original blister package in order to protect form moisture. Do not store above 30ºC.

You are advised to return expired medicine to your pharmacist.