Jedcomag is effervescent granules that contains magnesium citrate, an osmotic laxative that works by holding back fluid in the bowl to provide a wash-out effect.
Magnesium citrate also helps to prevent calcium oxalate crystals which are due to excessive diet containing oxalates (exogenous) or as a result of end products of metabolism (endogenous).

Jedcomag solution contains Citrate ions which chelate Calcium and make the urine alkaline thus help to prevent aggregation of oxalate crystals.

Indications
• Jedcomag is used in adults and adolescents as a purgative laxative to clean the bowel before an x-ray examination and endoscopy.
• Adjuvant therapy to dissolve Calcium Oxalate stones.

 Are allergic to Magnesium Oxide/ Citric acid or any of other ingredients of this medicine
 Have reduced ability of the stomach to empty ( gastric retention )
 Have stoch or intestinal ulcers
 Have severe problems with your kidneys
 Have a blockage or perforation of your bowel
 Are currently suffering from feeling or being sick
 Have a condition requiring abdominal surgery such as acute appendicitis
 Have been told by your doctor that you have congestive heart failure ( the heart is unable to pump blood efficiently around the body )
 Have active inflammatory bowel disease such as Crohn’s disease or ulcerative colitis
 Have been told by your doctor that you have too much magnesium in your blood
 Are very thirsty or may be severely dehydrated.
 Have been told by your doctor that you have damaged muscles that are leaking their contents to your blood.
 Have a condition called :
- Ileus ( intestinal blockage or failure of normal bowel movements )
- Toxic colitis ( damage to the intestinal wall)
- Toxic megacolon ( expansion of the large bowl)
In these conditions, the movement of the contents of the bowel may be impaired or prevented. Symptoms include nausea, vomiting, diarrhea, abdominal pain, tenderness or swelling, colicky pain and fever
Warnings and precautions
Talk to your doctor or pharmacist before taking Jedcomag:
• If you had recently had abdominal surgery
• If you have a heart disease or kidney problems
• If you have inflammatory bowel disease such as ulcerative colitis or Crohn’s disease
• If you are younger than 18 years, elderly or physically week. You should make sure to drink a sufficient amount of fluid and electrolytes during the course of treatment
• If you are taking Jedcomag prior to surgery involving the bowel
• If you are suffering hypertension because Jedcomag solution yields considerable amount of sodium.
If you have an early time of the day procedure, you might need to take the second dose during night and possible sleep disturbance may occur.
Other medicines and Jedcomag
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
It is especially important to tell your doctor if you are taking:
• Bulk forming laxatives e.g. Bran
• Prescribed oral medication, especially if they are regularly prescribed as their effects may be modified e.g. contraceptives, antibiotics, ant diabetics, iron, penicillamine or antiepileptic. These medicines should be taken at least 2 hours before and not less than 6 hours after administration of Jedcomag
• Prescribed medication that may affect water and/or electrolyte balance e.g. water tablets, steroids, lithium, digoxin, antidepressant, carbamazepine or anti-psychotics.
Pregnancy, breast-feeding and fertility
If you are pregnant or breast-feeding, think you may be pregnant or are trying to have a baby, ask your doctor or pharmacist for advice before taking this medicine
Driving and using machines
Jedcomag has no effect on the ability to drive and use machines. However, you should make sure that you have access to a toilet at all times following each dose until the effect wears off.

Always take Jedcomag exactly as your doctor told you. Check with your doctor if you are not sure.
Jedcomag granules should be dissolved in a cup of cold water and taken during effervescence.
Dosing For Bowel Evacuation
Adults (including elderly) and children 9 and over
The recommended dose is 4 sachets taken 10 to 18 hours before your procedure and four
sachets to be taken 4 to 6 hours before your procedure.
The first dose taken should be followed by at five 250 ml drinks of clear liquids spread over several hours and the second dose taken, should be followed by at least three 25o ml drinks of clear liquids until 2 hours before procedure.
Children (under 9 years)
For the timing of dosing in children, refer to the instructions given for adults
From 1 and below 2 years: first dose is one sachet and second dose is one sachet.
From 2 and below 2 years: first dose is 2 sachets and second dose is 2 sachets.
From 4 and below 9 years: first dose is one 4 sachets and second dose is 2 sachets
For every one sachet of Jedcomag, 50 ml water is required to dissolve.
You should expect frequent, loose bowel motions to start at any time after taking a dose of Jedcomag. Please ensure that you have access to a toilet at all times following each dose, until the effects wear off.
In order to replace fluid lost from the body, it is important to drink plenty of clear liquids throughout the treatment with Jedcomag until the bowel movement has ceased. in general you should try to drink clear liquids when you are thirsty.
Clear liquids should include a variety of fruit juice without pulp, soft drinks, clear soup, tea, coffee (without milk, soy or cream) and water. Do not drink only water.
The success of your hospital procedure that you undergo depends on the bowel being as clear as possible. The procedure may need to be repeated if you do not achieve a clear bowel. You should always follow the dietary instructions given by your doctor.
Dosing for dissolving Calcium Oxalate Crystals:
- Adults: one sachet three times daily for one week or as directed by the physician.
If you take more Jedcomag than you should
If you have taken more Jedcomag than you should, contact your doctor immediately or go to the casualty department at your nearest hospital.
If you forget to take Jedcomag
Please consult your doctor, nurse or pharmacist for advice.

Like all medicines, this medicine can cause side effects, although not everybody gets them. There have been isolated reports of severe prolonged abdominal pain in some patients which may indicate a serious condition and require urgent medical care, and isolated reports of severe allergic reactions which may lead to difficulty in breathing.
Isolated cases of mild ulcers in the small bowel have also been reported.
In the case of allergic reaction or severe prolonged abdominal pain, contact your doctor or nearest casualty department immediately.
The known side effects of Jedcomag are described below:
Common (affects less than 1 in 100 but more than 1 in 100 patients):
• Headache
• Nausea
• Proctalgia ( anal pain)
Uncommon (affects less than 1 in 100 but more than 1 in 1000 patients):
• Rash and/or itching
• Vomiting and severe diarrhea can lead to dehydration with headache and confusion without proper fluid and salt replacement
• Abdominal pain
• Vomiting
• Low levels of potassium in the blood (hypokalemia) with or without associated fits. Fits have occasionally been reported in epileptic patients.
Other side effects for which the occurrence is not known:
• As the primary clinical effect, very regular, loose bowel movements, or diarrhea may happen. However, if your bowel movements become troublesome or give you concern , you should contact your doctor
if any of the side effects gets serious, or if you noticed any side effects not listed in the leaflet, please tell your doctor or pharmacist.

- Keep this medicine out of the reach and sight of children.
- Store below 30o C Keep out of light and moisture.
- Store in the original package.
- Do not use this medicine after the expiry date which is stated on the carton and sachet. The expiry date refers to the last day of that month.
- Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.