Ciproquin tablet contains the active substance ciprofloxacin. Ciprofloxacin is an antibiotic belonging to the fluoroquinolone family. It works by killing bacteria that cause infections. It only works with specific strains of bacteria.
It is used in adults to treat:
-  Respiratory tract infections.
-  Long lasting or recurring ear or sinus infections.
-  Urinary tract infections.
-  Genital tract infections in men and women.
-  Gastro-intestinal tract infections and intra-abdominal infections.
-  Skin and soft tissue infections.
-  Bone and joint infections.
-  To prevent infections due to the bacterium Neisseria meningitides, anthrax inhalation exposure.

-  It may be used in the management of patients with low white blood cell counts who have a fever that is suspected to be due to a bacterial infection.
- If you have a severe infection or one that is caused by more than one type of bacterium, you may be given additional antibiotic treatment in addition to ciprofloxacin.
-  It is used in children and adolescents, under specialist medical supervision, to treat lung and bronchial infections in children and adolescents suffering from cystic fibrosis, complicated urinary tract infections, including infections that have reached the kidneys, anthrax inhalation exposure.
-  It may also be used to treat other specific severe infections in children and adolescents when your doctor considered this necessary.
 

 Do not take Ciproquin tablet : 
-  If you are allergic (hypersensitive) to ciprofloxacin or to other quinolone drugs, or any of the other ingredients of Ciproquin tablet, listed in section 6 below.

Take special care with Ciproquin tablet : 
-   If you have ever had kidney problems because your treatment may need to be adjusted.
-   If you suffer from epilepsy or other neurological conditions.
-   If you have a history of tendon problems during previous treatment with antibiotics such as ciprofloxacin.
-   If you are diabetic because you may experience a risk of hypoglycaemia with ciprofloxacin,
-   If you have heart problems. Caution should be taken when using ciprofloxacin, if you were born with or have family history of prolonged QT interval (seen on ECG, electrical recording of the heart), have salt imbalance in the blood (especially low level of potassium or magnesium in the blood), have a very slow heart rhythm, have a weak heart, have a history of heart attack, you are female or elderly or you are taking other medicines that result in abnormal ECG changes. If you or a member of your family is known to have a deficiency in glucose-6-phosphate dehydrogenase, since you may experience a risk of anaemia with ciprofloxacin.
-  For the treatment of some genital tract infections, your doctor can prescribe another antibiotic in addition to ciprofloxacin. If there is no improvement in symptoms after 3 days of treatment, please consult your doctor.

Taking/using other medicines, herbal, or dietary supplements
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. This is because these medicines may affect the way Ciproquin works. Also, Ciproquin may affect the way these medicines work.

 -  Do not take Ciproquin together with tizanidine, because this may cause side effects such as low blood pressure and sleepiness.
 -  The following medicines are known to interact with ciprofloxacin in your body: Vitamin K antagonists or other oral anti-coagulants, probenecid, methotrexate, theophylline, tizanidine, olanzapine, clozapine, ropinirole, phenytoin, metoclopramide, cyclosporine, other medicines that can alter your heart rhythm, tricyclic antidepressants, some antimicrobials (that belong to the group of macrolides), some antipsychotics, zolpidem.
-  Ciprofloxacin may increase the levels of the following medicines in your blood: pentoxifylline, caffeine, duloxetine, lidocaine, sildenafil, agomelatine.
-  Some medicines reduce the effect of Ciproquin.
-  Tell your doctor if you take or wish to take: antacids, omeprazole, mineral supplements, sucralfate, a polymeric phosphate binder, medicines or supplements containing calcium, magnesium, aluminium or iron. If these preparations are essential, take Ciproquin about two hours before or no sooner than four hours after them.
Taking Ciproquin tablet with food and drink
Unless you take Ciproquin during meals, do not eat or drink any dairy products (e.g. Milk or yoghurt) or drinks with added calcium when you take the tablets, as they may affect the absorption of the active substance.

Pregnancy and breast-feeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. It is preferable to avoid the use of ciprofloxacin during pregnancy. Do not take ciprofloxacin during breast-feeding because it is excreted in breast milk and can be harmful for your child.
Driving and using machines
Ciprofloxacin may make you feel less alert. Some neurological adverse events can occur. Therefore, make sure you know how you react to it before driving a vehicle or operating machinery. If in doubt, talk to your doctor.
Important information about some of the ingredients of Ciproquin tablet
This medicine contains lactose, so patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose- galactose malabsorption should not take this medicine.
 

- Always take Ciproquin tablet exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. Your doctor will explain to you exactly how much Ciproquin you will have to take as well as how often and for how long. This will depend on the type of infection you have and how bad it is.
- Tell your doctor if you suffer from kidney problems because your dose may need to be adjusted. The treatment usually lasts from 5 to 21 days, but may take longer for severe infections.
- Swallow the tablets with plenty of fluid. Do not chew the tablets because they do not taste nice, do try to take the tablets at around the same time every day, you can take the tablets at mealtimes or between meals. Any calcium you take as part of a meal will not seriously affect uptake.

If you take more Ciproquin tablet than you should
If you take more than the prescribed dose, get medical help immediately. If possible, take your tablets or the box with you to show the doctor.

If you forget to take Ciproquin tablet
If you forget to take your dose on time, take it as soon as you remember unless it is nearly time for your next dose. Do not take a double dose to make up for a forgotten dose.
If you stop taking Ciproquin tablet
It is important that you finish the course of treatment even if you begin to feel better after a few days. If you stop taking this medicine too soon, your infection may not be completely cured and the symptoms of the infection may return or get worse. You might also develop resistance to the antibiotic.

If you have any further questions on the use of this product, ask your doctor or pharmacist.
 

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Stop taking ciprofloxacin and see a doctor or go to a hospital immediately in order to consider another antibiotic treatment if you notice the following side effects:

Rare (may affect up to 1 in 1,000 people):
Seizure
Very rare (may affect up to 1 in 10,000 people):
Severe, sudden allergic reaction with symptoms such as tightness in the chest, feeling dizzy, sick or faint, or experience dizziness when standing up (anaphylactic reaction/shock), muscle weakness, inflammation of the tendons which could lead to rupture of the tendon, particularly affecting the large tendon at the back of the ankle, a serious life-threatening skin rash, usually in the form of blisters or ulcers in the mouth, throat, nose, eyes and other mucous membranes such as genitals which may progress to widespread blistering or peeling of the skin.
Other side effects which have been observed during treatment with ciprofloxacin are listed below by how likely they are:
Common (may affect up to 1 in 10 people):
Nausea, diarrhea, joint pain and joint inflammation in children.
Uncommon (may affect up to 1 in 100 people):
Joint pain in adults, fungal superinfections, a high concentration of eosinophils, a type of white blood cell, decreased appetite, hyperactivity or agitation, headache, dizziness, sleeping problems, or taste disorders, vomiting, abdominal pain, digestive problems such as (indigestion/heartburn), or wind, increased amounts of certain substances in the blood (transaminases and/or bilirubin), rash, itching, or hives, poor kidney function, pains in your muscles and bones, feeling unwell, or fever, increase in blood alkaline phosphatase (a certain substance in the blood).
Rare (may affect up to 1 in 1,000 people):
Muscle pain, inflammation of the joints, increased muscle tone and cramping, inflammation of the bowel linked to antibiotic use (can be fatal in very rare cases), changes to the blood count, increased or decreased amounts of a blood clotting factor, allergic reaction, swelling, or rapid swelling of the skin and mucous membranes, increased blood sugar, decreased blood sugar, confusion, disorientation, anxiety reactions, strange dreams, depression, or hallucinations, pins and needles, unusual sensitivity to stimuli of the senses, decreased skin sensitivity, tremors, or giddiness, eyesight problems including double vision, tinnitus, loss of hearing, impaired hearing, rapid heartbeat, expansion of blood vessels, low blood pressure, or fainting, shortness of breath, including asthmatic symptoms, liver disorders, jaundice, or hepatitis, sensitivity to light, kidney failure, blood or crystals in the urine, urinary tract inflammation, fluid retention or excessive sweating, increased levels of the enzyme amylase.
Very rare (may affect up to 1 in 10,000 people):
A special type of reduced red blood cell count; a dangerous drop in a type of white blood cells; a drop in the number of red and white blood cells and platelets, which may be fatal; and bone marrow depression, which may also be fatal, allergic reaction called serum sickness-like reaction, mental disturbances, migraine, disturbed coordination, unsteady walk, disorder of sense of smell, pressure on the brain, visual colour distortions, inflammation of the wall of the blood vessels, pancreatitis, death of liver cells very rarely leading to life-threatening liver failure, small, pin-point bleeding under the skin; various skin eruptions or rashes, worsening of the symptoms of myasthenia gravis.

If you get any side effects, or if you notice any side effects not listed in this leaflet, talk to your doctor or pharmacist.
 

• Keep out of the reach and sight of children.
• Store below 30 ◦ C. Store in the original packaging
• Do not use Ciproquin tablet after the expiry date which is stated on the carton and blister. The expiry date refers to the last day of that month.
• Medicines should not be disposed of via waste water or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment