TESTAVAN® is a clear gel that contains testosterone, a male hormone produced naturally in your body.
TESTAVAN® is used to replace testosterone in adult men when you do not produce enough natural testosterone – this is called “hypo-gonadism”. The medicine helps to raise your testosterone to normal levels.

What testosterone does
Testosterone is made naturally in your body in your testicles.
- It helps produce sperm and to develop and maintain male features such as a deep voice and body hair.
- It is necessary for normal sexual function and sex drive.
- It also helps to maintain muscle size and strength.

What TESTAVAN® is used for
TESTAVAN® is used in men for testosterone replacement to treat various health problems caused by a lack of testosterone (male hypogonadism). This should be confirmed by two separate blood testosterone measurements and also include clinical signs and symptoms such as:
- Impotence
- Infertility
- Low sex drive
- Tiredness
- Depressive moods
- Bone loss caused by low hormone level

- Partial loss of secondary sex characteristics, such as changes in your voice, changes in the fat distribution
- And partial loss of face and body hair

Who can use TESTAVAN®
- Only men can use TESTAVAN®.
- Young men under the age of 18 years should not use this medicine.
- This medicine should not be used by females of any age.
- Do not allow women (especially women that are pregnant or breast-feeding) or children to come into contact with TESTAVAN® gel or the areas of skin where TESTAVAN® has been applied.
Do not use TESTAVAN®
- if you are allergic to testosterone or any of the other ingredients of this medicine.
- if you have or are suspected of having prostate cancer.
- if you have or are suspected of having breast cancer (a rare condition for men).

Warnings and precautions
Testosterone treatment can speed up the progress of pre-existing prostate cancer. Your doctor will do the necessary tests before you can use TESTAVAN® and do follow-up check by carrying out periodic blood tests and prostate examinations.

Talk to your doctor or pharmacist before using TESTAVAN®, if any of the following applies to you:
- You have difficulty in passing water (urinating) due to an enlarged prostate gland.
- You have bone cancer - your doctor will check your calcium levels.
- You have high blood pressure, or if you are treated for high blood pressure, as testavan® may cause a rise in blood pressure.
- You have severe heart, liver or kidney disease, as treatment with testavan® may cause severe complications in the form of water retention in your body sometimes accompanied by (congestive) heart failure (fluid overload in the heart).
- You have ischaemic heart disease (which affects the supply of blood to the heart).
- You have a blood clotting problems called (thrombophilia) (a problem of blood coagulation – this increases the risk of getting blood clots in your blood vessels (thrombosis).
- You have epilepsy.
- You have migraines.
- You have breathing difficulties when you sleep - these are more likely to happen if you are overweight or have long term lung problems.

If any of the above apply to you (or you are not sure), talk to your doctor or pharmacist before using TESTAVAN®– using this medicine may make these conditions worse.
If you develop reactions on your skin where you applied the TESTAVAN®, go back to your doctor to seek advice. It may be necessary to stop the treatment with TESTAVAN®.
The following blood checks should be carried out by your doctor before and/ or during the treatment: testosterone blood levels, full blood count.
At the time of, and just after, the daily application of TESTAVAN®, do not apply moisturisers or sunscreen products to the area where you have put the gel.

How to prevent transfer of TESTAVAN® to someone else
TESTAVAN® can transfer to others by close skin-to-skin contact. This may result in increased testosterone levels in their body – this can be dangerous. This can happen from one contact – but it can also build up bit by bit with small amounts of contact over time.
- This is especially important for women and children – they normally only have low levels of testosterone in their bodies.

- Pregnant women must not come into contact with TESTAVAN®. If your partner is pregnant you must be careful and protect her from any contact with the medicine and the application area.
To stop the gel being transferred from your skin to someone else, you should:
- use the applicator to apply the medicine rather than your fingers.
- wash your hands with water and soap straight away if you do get any TESTAVAN® on your hands.
- cover where you have put the gel with clothing - once the gel has dried.
- have a bath or shower, or wear clothing to cover the gel application site (such as a T-shirt), before having close skin-to-skin contact with anyone.

What to do if someone else is exposed to TESTAVAN®
If someone touches the gel or has skin-to-skin contact where you have put the gel, they should wash their area of skin with soap and water as soon as possible. The longer that the gel is in contact with the skin before washing, the greater the chance that the person will absorb some testosterone.
If TESTAVAN® has been transferred to someone else, then look out for any changes in the body or behaviour of people close to you. If anyone close to you gets any of the following signs, they should see their doctor:
- Acne.
- Deepening of the voice.
- Growth of facial or body hair.
- Changes in their monthly period.
- Early puberty, genital enlargement or changes in level of sexual behaviour of children.

Other medicines and TESTAVAN®
Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines. This includes medicines obtained without a prescription and herbal medicines. TESTAVAN® may affect how these medicines work and you may need to have your doses adjusted.
In particular, tell your doctor or pharmacist if you are taking:
- Medicines to thin your blood (anti-coagulants)- TESTAVAN® may increase the effects of these drugs.
- Corticosteroids or any other medicines that may increase the production of these hormones. Both corticosteroids and TESTAVAN® may cause your body to hold on more water.
- Insulin to control your blood sugar levels (in diabetes); you may need to reduce your dose of insulin when you are in treatment with TESTAVAN®.
If any of the above apply to you (or you are not sure), talk to your doctor or pharmacist before using TESTAVAN®.

Pregnancy, breast-feeding and fertility
TESTAVAN® is not intended for use by pregnant or breastfeeding women.
If your partner is or becomes pregnant, you must follow the advice above under the heading ‘How to
prevent transfer of TESTAVAN® to someone else’.
Pregnant women must avoid any skin contact with TESTAVAN® application sites in men. This medicine may cause damage to the unborn baby. In the event of contact, the area should be washed as soon as possible with soap and water.
Breast-feeding women must avoid any contact with TESTAVAN® application sites in men.

Sperm production may be reversibly suppressed with TESTAVAN®.
TESTAVAN® contains propylene glycol
This medicine contains propylene glycol, which may cause skin irritation.

Always use this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
How much to use
- The recommended starting dose of TESTAVAN® is 23 mg testosterone (one pump press) applied once daily at approximately the same time each day preferably in the morning- but some patients may require a higher dose.
- The maximum recommended dose is 69 mg testosterone daily (three pump presses).
The correct dose of TESTAVAN® that you need will be decided by your doctor – they will do this by measuring two things regularly:
- the levels of testosterone in your blood
- How well the medicine is working for you.
Talk to your doctor if you feel that the effects of the medicine is too strong or too weak.
Using this medicine
It is important that you read and follow these directions on how to use TESTAVAN® properly.
Apply TESTAVAN® on your skin using the applicator. This is called “trans-dermal use” – the medicine goes through your skin into your body.
Apply the medicine only to clean, dry, normal healthy skin on your shoulders and upper arms.
Never apply TESTAVAN® to:
- Your penis and testicles
- To skin that is broken or damaged
- Open sores, wounds or irritations.

Supplies you will need

Step 3: Cleaning your TESTAVAN® applicator
• After use, clean the applicator with a tissue. See Picture I.

If you use more TESTAVAN® than you should
If you have applied too much medicine by mistake, wash the application area with soap and water as soon as you realise.
Only use the amount of medicine prescribed by your doctor. If you feel irritable, nervous, gain weight, get long lasting or frequent erections – these may be signs that you are using too much.
If you forget to use TESTAVAN®
Do not use a double dose to make up for a forgotten dose.
- If your next dose is less than 12 hours away, do not take the missed dose. Then take your next dose as normal.
- If it is more than 12 hours until your next dose, take the dose that you have missed. Continue as normal the following day.
If you stop using TESTAVAN®
Talk to your doctor before you stop taking this medicine.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Common (may affect up to 1 in 10 people)
• skin irritation where the gel has been applied (including rash, dryness and redness)
• high levels of fats (triglycerides) in the blood
• increased blood pressure
• increased Prostatic Specific Antigen (PSA). PSA is a protein produced by the prostate, which can be used to detect prostate disease
• increased haematocrit (percentage of red blood cells in blood), identified by periodic blood tests
Uncommon (may affect up to 1 in 100 people)
• Increased haemoglobin (the component of red blood cells that carries oxygen), identified by periodic blood tests.
• Headache.

Other known undesirable effects associated with testosterone treatment include:
acne, seborrhoea, baldness, sweating, increased body hair growth, skin tickling or numbness, headache, dizziness, nausea, hot flushes, fluid retention (such as swelling of ankles), weight gain, sleep apnoea, shortness of breath, hypersensitivity reactions, feeling sick/ unwell, changes to your mood (such as aggression, hostility, nervousness, anxiety, depression), sleeplessness, muscular pain or cramp, development of breasts, increase in red blood cell count, decrease in red blood cells, blood clots, jaundice (liver problems which sometimes may be associated with yellowing of the skin and the whites of the eyes), abnormal liver function tests.
Sex drive changes, erection increased, priapism (prolonged and painful erections), testis disorder, reduced number of sperm, difficulty passing urine, changes to your prostate gland, prostate cancer (there is no convincing evidence that testosterone replacement in hypogonadal men induces prostate cancer; however, testosterone therapy is to be avoided in men already known or thought to have prostate cancer).
Prolonged testosterone administration may cause changes in the levels of salts (electrolytes) and water in the body.

Keep this medicine out of the sight and reach of children.

Store below 30°C.
This product must be used within 2 months after opening .
Storage conditions after opening : Store below 30°C.
Do not use this medicine after the expiry date which is stated on the pump label and the outer carton after Exp. The expiry date refers to the last day of that month.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.