Iphen™ eye drops contains a mydriatic agent. It is used to enlarge the pupil of your eye.
Your doctor or eye specialist may use it to examine your eye more closely or as part of a
treatment program.
Iphen™ eye drops 10% is not indicated for children or the elderly, as this concentration is
too strong. The doctor or eye specialist will use an alternative medicine in these patients

Do not use Iphen™ eye drops drops if:
• you are allergic to the active substance (phenylephrine) or any of the other ingredients of
this medicine (listed in section 6)
• you have a heart disease
• you have fast heartbeats (tachycardia)
• you have high blood pressure
• you have bulges in major blood vessels (aneurysms)
• you have an overactive thyroid gland (hyperthyroidism)
• you have high blood sugar level (diabetes mellitus)
• Patients on monoamine oxidase inhibitors, tricyclic antidepressants and anti-hypertensive
agents (including beta-blockers)
• Patients with closed angle glaucoma (unless previously treated with iridectomy) and
patients with a narrow angle prone to glaucoma precipitated by mydriatics
• Use in patients wearing contact lenses.
Warnings and precautions
Use with caution in children and the elderly.
Ask yourself the following questions:
• Do you have narrow arteries in the head (cerebral arteriosclerosis)?
• Do you have asthma?
• Do your eyes develop increased internal pressure when the pupil is enlarged? The doctor
or eye specialist will have checked to make sure that this problem will not affect you.
• Are your eyes red or inflamed?
If the answer to any of these questions is yes, tell your doctor or eye specialist.
The active substance can cause the cornea to become cloudy if the surface of the cornea is
damaged. The cornea is the transparent membrane covering the surface of the eye. Your
doctor or eye specialist will take this into account before deciding to give you these eye
drops.
Other medicines and Iphen™ eye drops
Tell your doctor or eye specialist if you are taking, have recently taken or might take any
other medicines.
• Medicines for depression
• Any medicines to reduce your blood pressure (including medicines called betablockers)
• Medicines to treat irregular heartbeats (quinidine or medicines called cardiac glycosides)
The active substance can react with several types of anaesthetic (e.g. halothane). Your
doctor will know about this. If you are having an operation your doctor will make sure that
this problem does not affect you.
Pregnancy, breast-feeding and fertility
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a
baby, ask your doctor or eye specialist for advice before taking this medicine as he/ she
may decide to use these drops or to prescribe you an alternative.
Contact lenses
Your doctor will ask you to remove your contact lenses prior to the administration of the
drops. There is no information on the effect of this product on contact lenses. Therefore, do
not wear your contact lenses until the effects of the drops have completely worn off.
Driving and using machines
Some people find bright light (such as daylight) uncomfortable for a few hours after
receiving Iphen™ eye drops.
This may make it difficult for you to drive. As with all eye drops, your vision may be
blurred after putting the drops in. Wait until your vision is clear before driving or using
machines.
3. How to use

Sometimes a drop of local anaesthetic may be used prior to Iphen™ eye drops to prevent the
stinging effect of phenylephrine eye drops. The drops are for single use only and provided
in single use Minims units, to treat both eyes if both eyes are affected. Once opened, use
immediately. Discard any unused portion.
Dosage
The recommended dose is one drop in each eye. If necessary this can be repeated once only
at least one hour after the first drop.
Iphen™ 10% w/v: For examination of the eye, the normal dose for adults is one drop in
each eye. Minims Iphen™ 10% w/v is not recommended for use in children or elderly
patients. If you are receiving this product as part of a treatment programme your doctor
may suggest an additional dose schedule of one drop every 24 hours of the 2.5% w/v
product.
Method of administration
The doctor or eye specialist will normally put the drops in your eye for you, but if you are
putting the eye drops in yourself, then follow these instructions carefully:
1. Wash your hands.
2. Use a mirror, this will help you to see what you are doing.
3. Carefully dry your eyes using a tissue. Twist and pull cap
to separate from the Minims body (Diagram 1).
4. Pull your lower eyelid down gently, and then carefully place
1 drop inside your lower eyelid.
5. Close your eye and blink a few times to make sure your eye is covered by the liquid.
6. Close the eyelids. It is advisable to press gently on the inner corner of your eyelid for
3 minutes. This will help stop the solution draining into your nose and throat.
7. Repeat steps 4, 5 and 6 for the other eye if necessary, then throw away the Minims unit,
even if some solution remains.

If you use more Iphen™ eye drops than you should, an overdose is very unlikely to
occur. If you suddenly feel unwell after receiving the drops, tell your doctor or eye specialist
or contact your nearest emergency department immediately.
If you forget to use Iphen™ eye drops, you should take the missed dose as soon as you
remember, unless it is nearly time for the next dose, but you should not take a double dose
to make up for a missed dose.

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Iphen™ eye drops may sting when the drops are first put in and your vision may become
blurred. This will gradually wear off.

Serious side effects
• Rarely,moreseriousreactions,including spasm of theartery of the heart, heart irregularities
and heart attacks, havebeenreportedafterusing phenylephrine solutions. These have usually
occurred in patients using some 10 % phenylephrine and already suffering from heart
disease.
Other side effects
Not known: frequency cannot be estimated from the available data.
• In some cases bright light can be uncomfortable for a few hours after receiving the drops.
• Occasionally allergic reactions or conjunctival sensitivity (abnormal sensitivity of the
conjunctiva (thin, clear, moist membrane that coats the white outer surface of the eye) to
various substances with discomfort upon instillation) can occur.
• The active substance can sometimes affect your circulatory system, causing increased
blood pressure and palpitations (a sensation in which a person is aware of an irregular, hard,
or rapid heartbeat), tachycardia (fast heartbeats) and other heart irregularities (extrasystoles
and cardiac arrythmias).
Additional side effects in children:
Not known: frequency cannot be estimated from the available data
• Fluid or swelling in the lungs (this is relevant to the 10% formulation).
Reporting of side effects
If you or your child get any side effects, talk to your doctor, the doctor treating your child or
pharmacist. This includes any side effects not listed in this leaflet. By reporting side effects
you can help provide more information on the safety of this medicine.

Keep this medicine out of the sight and reach of children.
Do not use the eye drops after the expiry date which is stated on the overwrap of each unit
and on the carton after the letters “EXP”.
Do not store above 25 °C.
Do not freeze. Store in the original package in order to protect from light.
The drops are for single use only and provided in single use Minims units, to treat both eyes
if both eyes are affected. Once opened, use immediately. Discard any unused portion.
Medicines should not be disposed of via wastewater or household waste.
Ask your pharmacist how to dispose of medicines no longer required. These measures will
help to protect the environment.