Lidapro medication is a topical cream used on the skin or in the genital area and belongs to local
anesthetics.
Lidapro topical cream is indicated for:
• Topical anaesthesia of the skin in connection with:
- Needle insertion, e.g. intravenous catheters or blood sampling;
- Superficial surgical procedures;
- In adults and in the paediatric population.
• Topical anaesthesia of the genital mucosa, e.g. prior to superficial surgical procedures or infiltration
anaesthesia; in adults and adolescents ≥ 12 years
• Topical anaesthesia of leg ulcers to facilitate mechanical cleansing/debridement in adults only.
 

Do not use Lidapro
• If you know you are allergic to lidocaine and/or prilocaine or local anesthetics of the amide type.
Warnings and precautions
Talk to your doctor or pharmacist before using Lidapro:
• if you or your child have a rare inherited illness that affects the blood called ‘glucose-6- phosphate
dehydrogenase deficiency’.
• if you or your child have a problem with blood pigment levels called “methemoglobinaemia”.
• if you or your child have an itchy skin condition called ‘atopic dermatitis’, a shorter
application time may be sufficient. Application times of longer than 30 minutes may result in an
increased incidence of local skin reaction.
• if you take particular products for heart rhythm disorders (class III antiarrhythmics, such as
amiodarone). In that case the doctor will monitor your heart function.
Do not use Lidapro on areas with skin rash, cuts, grazes or other open wounds, with the exception of a
leg ulcer. If any of these problems are present, check with your doctor, pharmacist or nurse before
using the cream.
Pediatric population
Lidapro should not be used
• in newborn infants/infants up to 12 months of age receiving concomitant treatment with
methemoglobin-inducing agents.
• in preterm newborn infants with a gestational age less than 37 weeks as they are at risk of
developing increased methemoglobin levels.
Safety and efficacy for the use of Lidapro on genital skin and genital mucosa have not been established
in children younger than 12 years.
• Specific interaction studies in children have not been performed. Interactions are likely to be similar
to the adult population.
Other medicines and Lidapro
Tell your doctor or pharmacist if you are taking, have recently taken or might take any of the following
medicines:
• Medicines used to treat infections, called ‘sulphonamides’ and nitrofurantoin.
• Medicines used to treat epilepsy, called phenytoin and phenobarbital.
• Other local anaesthetics.
• Medicines to treat an uneven heartbeat, such as amiodarone.
• Cimetidine or beta-blockers, which may cause an increase in the blood levels of lidocaine. This
interaction is of no clinical relevance in short-term treatment with Lidapro in recommended doses.
Pregnancy and breastfeeding
If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask
your doctor or pharmacist for advice before using this medicine.
Occasional use of Lidapro during pregnancy is unlikely to have any adverse effects on the foetus.
The active substances in Lidapro are passed into breast milk. However, the amount is so small that
there is generally no risk to the child.
Driving and using machines
Lidapro has no or negligible influence on the ability to drive and use machines when used at the
recommended doses.

Adults and adolescents 12 years of age and above Skin
• Minor procedures, e.g. needle insertion and surgical treatment of localised lesions: 2 g (approx half a
5 g tube) or approx. 1.5 g/10 cm2 for 1 to 5 hours.
• Dermal procedures on newly shaven skin of large body areas, e.g. laser hair removal
(self- application by patient): Maximum recommended dose: 60 g. Maximum recommended treated
area; 600 cm2 for a minimum of 1 hour, maximum 5 hours.
• Dermal surgical procedures on larger areas in a hospital setting, e.g. split-skin grafting: Approx 1.5-2
g/10 cm2 for 2 to 5 hours.
• Skin of male genital organs-Prior to injection of local anaesthetics: 1 g/10 cm2 for 15 minutes.
• Skin of female genital organs-Prior to injection of local anaesthetics: 1-2 g/10 cm2 for 60 minutes.
Genital mucosa
• Surgical treatment of localised lesions, e.g. removal of genital warts (condylomata acuminata) and
prior to injection of local anaesthetics: approx 5-10 g of cream for 5-10 minutes.
• Prior to cervical curettage: 10 g of cream should be administered in the lateral vaginal fornices for 10
minutes.
Leg ulcer(s)
• Mechanical cleansing/debridement: approx 1-2 g/10 cm2 up to a total of 10 g to the leg ulcer(s).
Application time: 30-60 minutes.
Pediatric patients 0-11 years of age
• Newborn infants and infants 0-2 months: up to 1 g and 10 cm2 for one hour
• Infants 3-11 months: up to 2 g and 20 cm2 for one hour
• Toddlers and children 1-5 years: up to 10 g and 100 cm2 for 1-5 hours
• Children 6-11 years: up to 20 g and 200 cm2 for 1-5 hours
• Pediatric patients with atopic dermatitis: application time: 30 minutes
Presentation:
Lidapro cream is available in a pack contains
5 x 5g aluminum tube along with 5 sterile transparent dressings.
Instructions for application of sterile transparent dressings
1. Open package and remove sterile dressing.

2. Apply the amount of cream to each site as instructed.

3. Peel the liner paper from the dressing.
4. Cover the cream, holding into dressing frame. Smooth down the edges of the dressing carefully to
avoid leaking.
5. Slowly remove the paper frame.
6. After application, slowly remove the dressing from the skin in the direction of hair growth. Wipe
off the cream and clean the entire area.

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Common side effects
• Transient local skin reactions (paleness, redness, swelling) in the treated area during treatment of
skin, genital mucosa or leg ulcers.
• An initially mild sensation of burning, itching or warmth at the treated area during treatment of
genital mucosa or leg ulcers.
Uncommon side effects
• An initially mild sensation of burning, itching or warmth at the treated area during treatment of the
skin.
• Numbness (tingling) in the treated area during treatment of genital mucosa.
• Irritation of the treated skin during treatment of leg ulcers.
Rare side effects
• Methemoglobinaemia
• Hypersensitivity
• Corneal irritation
• Purpura, Petechiae (especially after longer application times in children with atopic dermatitis or
mollusca contagiosa)
Pediatric population
Frequency, type and severity of adverse reactions are similar in the pediatric and adult age groups,
except for methemoglobinaemia, which is more frequently observed, often in connection with
overdose, in newborn infants and infants aged 0 to 12 months.

Keep this medicine out of the sight and reach of children.
Do not store above 30°C and do not freeze.
Do not use this medicine after the expiry date which is stated on the package and tube after
‘EXP:’. The expiry date refers to the last day of that month.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist
how to throw away medicines you no longer use. These measures will help protect the
environment.